Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Jordan.

نویسندگان

  • Naif S Karadsheh
  • Linda Moses
  • Said I Ismail
  • Joseph M Devaney
  • Eric Hoffman
چکیده

Molecular screening for glucose-6-phosphate (G6PD) mutations in two Jordanian populations revealed six different mutations and higher incidences of G6PD deficiency and G6PD A- (376A-->G + 202G-->A) mutation in Jordan Valley than in the Amman area. These observations may be explained by historically higher rates of malaria and African ancestral origins, respectively.

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عنوان ژورنال:
  • Haematologica

دوره 90 12  شماره 

صفحات  -

تاریخ انتشار 2005